SARS, coronavirus, antibiotic resistant bacteria, Lyme disease, West Nile Virus, lead poisoning, pesticides, disease reservoirs, and environmental conditions are just a few of the concerns and factors addressed in the transdisciplinary “One Health” approaches to enhance prevention and therapeutic care for humans and animals discussed in the book, Human-Animal Medicine: Clinical Approaches to Zoonoses, Toxicants and Other Shared Health Risks. This timely, valuable book by Doctors Peter M. Rabinowitz and Lisa A. Conti, along with many other authors, provides insights and guidance while calling for greater cooperation among human health and veterinary care providers.